Best Pet Stain and Odor Remover

Dog shaking dirty water over girl
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We’re not sure what’s worse, having to clean up a major mess, or having it leave behind a lasting stain. While our favorite stain and odor removing formulas sadly can’t eliminate the former, they can certainly help out when it comes to the latter. From sprays with enzyme-activated technology that eat away at even the deepest and toughest stains to solutions that hit stains and odors hard while still being gentle on you, these products will save your precious surfaces from permanent damage.

Top pick

Bottle of Pet Stain and Odor Remover

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Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator

If it’s horrible, it’s history

Say goodbye to stink and stains with this powerful stain and odor eliminator that can tackle anything from urine and feces to vomit and other spills. Go deep with this enzyme-activated formula that contains natural bacteria that are activated when they hit stains and feed on ammonia crystals and other organic matter until they’re gone. Gentle and effective, the spray is free from chlorine and certified safe for all carpets. It can also be used on floors, furniture, litter boxes, kennels, and carriers.

Best for tough stains

Bottle of Pet Stain and Odor Remover

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Simple Solution Extreme Pet Stain and Odor Remover

A formula that hits stains and odors hard

This professional strength formula is designed to handle the toughest pet stains and odors. The multi-functional 3-in-1 sprayer allows you to choose how you release the solution with mist for surface stains, foam for embedded stains, and stream for odor control. The pro-bacteria and enzyme formula breaks down and eliminates stains while neutralizing odors and preventing repeat marking by pets. Featuring a clean and refreshing scent, it works great on carpets and most water-safe surfaces.

Best for severe messes

Bottle of Pet Stain and Odor Remover

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Nature’s Miracle Advanced Stain and Odor Eliminator

Eliminate major messes with this hard-hitting stain remover

If you’ve got a serious mess on your hands, then this is the product you want. The powerful formula makes quick work of stains and odors from dog urine, feces, diarrhea, and vomit. Great for treated hardwood floors, carpets, tiles, and linoleum, this bacteria-based formula produces enzymes that eat away at severe stains and offending odors until they’ve been eradicated. It has a fresh scent, is fast drying, and discourages re-soiling.

Best for cat urine

Bottle of Pet Stain and Odor Remover

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Nature’s Miracle Urine Destroyer

Yellow stains don’t stand a chance

For those cats who sometimes miss the litter box or don’t make it outside in time, this standout product will get to work fast. Tough on cat urine and the yellow, sticky residue that comes along with it, this disinfectant eats away at liquid messes with its targeted urine enzymatic oxy-formula, killing bad bacteria and viruses as it goes. It’s safe to use on carpets, hardwood floors, furniture, and fabrics and has a light scent.

Best non-toxic formula

Bottle of Pet Stain and Odor Remover

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Biokleen Bac-Out Natural Enzyme Stain and Odor Remover

Tough on mess, gentle on you

With a unique blend of live-enzyme producing cultures, botanicals, and plant-based surfactants, this full-strength formula can remove even the toughest stains and odors while being free from common toxins like phosphates and petroleum solvents. It’s ultra-concentrated for less waste, hasn’t been tested on animals, and the packaging is fully recyclable. Free from artificial colors and fragrances, this is a great choice for those with chemical sensitivities and allergies or people who simply want to reduce their toxic load.

Great value

Bottle of Pet Stain and Odor Remover

(Image credit: Amazon)

OUT! Orange Oxy Stain and Odor Remover

Banish stains and neutralize odors with this affordable spray

If you’re after a product that hits stains and odors hard while being gentle on your wallet, then this spray offers great value for money. The powerful oxidizing formula will make stains vanish before your eyes and neutralize odors rather than covering them up. It works on all stains from vomit to blood, and the orange fragrance leaves behind a clean and fresh scent. It will work on both old and new stains and removes the pheromones that encourage pets to repeatedly mark in the same spot.

How to choose the best pet stain and odor remover

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If there’s a downside to being a pet parent, it’s the unsavory job of having to clean up accidental messes. Thankfully, there’s plenty of products on the market that can save your carpets and furniture while making clean up a breeze. Our favorite is Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, with its enzyme-activated formula that goes deep to remove even the toughest of stains. If choosing a non-toxic and eco-friendly formula is high on your list of importance, then you’ll love the Biokleen Bac-Out Natural Enzyme Stain and Odor Remover, a solution that’s free from many of the chemicals found in other products but still hits stains and odors hard.

For homes where cat urine is the main cause for concern, Nature’s Miracle Urine Destroyer is specifically formulated to get rid of yellow stains and the residue that comes with them. And for severe dog messes, we recommend Nature’s Miracle Advanced Stain and Odor Remover that eats away at major stains and odors and helps prevent re-soiling.


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